*Define efficacy, potency, therapeutic index, therapeutic window, tolerance and tachyphylaxis

• Enlist at least 2 drugs exhibiting tolerance and tachyphylaxis

• Describe graded-dose response curves with their clinical significance

• Describe quantal-dose response curves with their clinical significance

• What is a graded dose response relationship
• Which one is more important while selecting a drug for therapy?
• Efficacy and Potency in relation with EC50 and Emax
• The relation between drug concentration and drug effect
• What is the graded dose drug binding relationship cuirve
• What is Kd
• What is a quantal dose response relationship
• Which three values of the drugs are extracted from the experiments of quantal dose response relationship
• What is efficacy
• How is efficacy mainly determined
• Which sore response curve helps in measuring the efficacy
• partial agonists have lower maximal efficacy than full agonists.
• What is potency