• Define drug antagonism
  • Describe different types of drug antagonism with examples
  • Describe the clinical significance of drug antagonism

  • What is intrinsic activity
  • What is affinity
  • How is affinity related to potency
  • What are antagonists
  • What are inverse agonists
  • What are partial agonists
  • What is that specific property which the antagonists do not possess?
  • Antagonists maintain or disrupt the active inactive equilibrium?
  • Types of agonists
  • What are physiological antagonists?
  • What is the intrinsic activity of the physiological antagnist?
  • What is chemical antagonism
  • In chemical antagonism the chelator (sequester) interacts directly with what?
  • What is pharmacological antagonism?
  • Which receptors do antagonists compete for in pharmacological antagonism?
  • Does the Emax change for competitive antagonism